Benadryl side effects long term - Uses Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough,...

 
Sleep aids: The options. Sleep aids available without a prescription are widely available. Common choices and the potential side effects include: Diphenhydramine (Benadryl). Diphenhydramine is a sedating antihistamine. Side effects might include daytime drowsiness, dry mouth, constipation and urinary retention. Doxylamine (Unisom).. Charlid

This video examines the question and remark: Benadryl long term side effects! I WISH I had KNOWN! Benadryl is a common OTC medication and is also known as D...Section snippets Sedation. The sedation associated with diphenhydramine is one of the most acknowledged effects of this medication. Indeed, it is frequently used as a medication to treat insomnia. 3 The sedative effect of diphenhydramine is related to its easy penetration of the blood-brain barrier. 4 In the brain, diphenhydramine interferes with H 1 receptors, which causes drowsiness and ...Effects of Long-Term Diphenhydramine Use The information regarding the effects of prolonged Benadryl use is once again not known, as prospective studies analyzing its prolonged use do not exist. There are some exceptions to the above statement, however, the following are related to the long-term use of any antihistamine medication and ...Aug 1, 2023 · What are the side effects of Benadryl ... Diphenhydramine is only for short-term use until your symptoms clear up. ... (such as a long car ride, airplane or boat travel, amusement park rides, etc ... The active ingredient in Benadryl is called diphenhydramine. Like any medication, Benadryl has several side effects. Some of the most common are: feeling sleepy or drowsy. dry mouth or throat ...Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache.hoarseness. lack or loss of strength. pain in the lower back or side. swelling of the hands, feet, or lower legs. trembling or shaking. Common side effects that do require medical attention ...“Atarax (hydroxyzine) and Benadryl (diphenhydramine) were routinely administered in the chemotherapy I received for breast cancer. After 5 months of chemo, I attributed my loss of mental function to a condition I read about called “chemo brain” — and chalked it up as another price paid in side affects for the benefit of staying alive.Benadryl and Depression. Although there is no direct effect of Benadryl on depression, regular and daily use of Benadryl does result in severe depression in the individual. It is believed to be helpful only for the short term, however, long term use of Benadryl results in certain depressive symptoms in the individual.Dizziness Nausea or vomiting Loss of appetite Constipation Increased chest congestion Headache Excitability (especially in children) Nervousness Benadryl can impair mental and motor functioning, as well as your performance at work or school. It can also impair a person’s ability to operate a motor vehicle or other potentially dangerous equipment.While there are cases of misuse and abuse, withdrawal symptoms from Benadryl are rare, even with long term use. Nevertheless, Benadryl has strong anticholinergic effects, and there have been reports of 'anticholinergic withdrawal' in some individuals taking Benadryl for extended periods of time. Potential symptoms include:Section snippets Sedation. The sedation associated with diphenhydramine is one of the most acknowledged effects of this medication. Indeed, it is frequently used as a medication to treat insomnia. 3 The sedative effect of diphenhydramine is related to its easy penetration of the blood-brain barrier. 4 In the brain, diphenhydramine interferes with H 1 receptors, which causes drowsiness and ...Experts say skip antihistamines. Dana Benson. 713-798-8267. Houston, TX - Jun 28, 2021. Share this article. For people who take an antihistamine such as Benadryl for a cold or allergies, drowsiness is often a welcome side effect. But a Baylor College of Medicine sleep expert cautions against turning to this type of medication as a sleep aid.Diphenhydramine or : Benadryl (diphenhydramine) may cause sedation the next day (due to its long half-life), decreased alertness, diminished cognitive function, delirium, ... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5k views Reviewed >2 years ago. Yes, certain side effects may be possible with long-term use of Benadryl. However, doctors usually don’t recommend Benadryl for long-term use. Instead, they typically advise short-term use of the drug to ease certain symptoms. The drug’s label information* for Benadryl does not specify any long-term side effects for this drug.Jun 6, 2023 · Benadryl may cause serious side effects including: pounding heartbeats or fluttering in your chest, painful or difficult urination, little or no urination, confusion, lightheadedness, tightness in your neck or jaw, and. uncontrollable movements of your tongue. Get medical help right away, if you have any of the symptoms listed above. feeling of warmth, redness of the face, neck, arms and occasionally, upper chest. large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs. shortness of breath, difficult or labored breathing. Some side effects may occur that usually do not need medical attention.Adults and children ≥12 years of age receiving conventional or orally disintegrating tablets: Headache, somnolence, fatigue, dry mouth. Fixed combination loratadine (the active ingredient contained in Claritin) pseudoephedrine sulfate preparations: Insomnia, dry mouth, headache, somnolence, nervousness, dizziness, fatigue.Oct 9, 2018 · Many older adults may take sleeping pills because pain, nerve problems or other health issues are keeping them up at night, she says. For these people, a sleeping pill is standing in the way of ... Diphenhydramine is a type of medicine called an antihistamine. It is used in some allergy and sleep medicines. Overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. This article is for information only. DO NOT use it to treat or manage an actual overdose.Benadryl dosage for dogs. The correct dosage of diphenhydramine for dogs depends on their weight. A small dog will need much less than a big dog to receive the same positive effects. According to ...Mar 21, 2023 · There is very little scientific research about the long-term effects of Benadryl. Some side effects that may occur with long-term use include: constipation; blurred vision Diphenhydramine is a common ingredient in sleeping aids; it is also used to treat allergies. While effective, the risk of serious diphenhydramine side effects—including confusion, dizziness, urinary retention, and liver or kidney issues—is increased in people age 65 and older.Yes, certain side effects are possible after using Benadryl long term. For example, long-term use of Benadryl may cause: an increased risk of dementia; withdrawal symptoms after the drug is stopped* However, keep in mind that doctors typically don’t recommend taking Benadryl as a long-term treatment.Jun 23, 2009 · The most common side effect is drowsiness, causing mild disorientation or dementia. An elderly person may fall asleep during normal activities. This sedating effect can cause unsteadiness. A person over 60 should get up slowly from a sitting or prone position to avoid fainting. If you take an anti-anxiety drug, it is not advisable to use ... Diphenhydramine, brand name Benadryl ®, is one of the oldest and most frequently used over-the-counter medications for children. However, many better options are now widely available, all of which are faster acting, longer lasting, with less side effects. Antihistamines counteract the effect of histamine throughout the body, and treat a range ...Diphenhydramine blocks the effects of histamine in your brain and this reduces symptoms. It enters the brain in large quantities and this can make you feel drowsy. Diphenhydramine also blocks the effects of another chemical called acetylcholine. This can help a cough or runny nose but can also cause side effects such as a dry mouth and dry nose.Yeah, look at r/dph.Datura is even worse. It's like dph, but way more likely to kill you or make you go blind. Shadow people and spiders and having full conversations with people who don't exist usually only happens in the 400+ category. Between 150mg and there, it's usually just having to piss but being unable to, dysphoria/fear, be Jun 14, 2023 · The symptoms you have noticed are very likely the result of long-term heavy antihistamine use. Antihistamines tend to dry up the nose, which is why they are so effective in humans with allergic rhinitis, but the way they do that is by making the secretions thicker. In dogs, we are not worried much about a runny nose, but we are concerned about ... • Common side effects of montelukast include upper respiratory infection, fever, headache, sore throat, cough, stomach pain, diarrhea, earache or ear infection, flu, runny nose, and sinus infection.Higher dosage or long-term use of common drugs with anticholinergic effects is linked to significantly increased risk of dementia - including Alzheimer’s - says large study.May 17, 2018 · Answer From Eric J. Olson, M.D. It's unlikely you'll become dependent on zolpidem (Ambien). Ambien and similar sleep medications can be effective, and they're much less likely to be habit-forming than some other drugs sometimes prescribed for sleep problems — for example, benzodiazepines, such as alprazolam (Xanax), lorazepam (Ativan) or ... Pay attention to the side effects of Benadryl, especially if you’re an older adult. The body responds differently to Benadryl as you get older. And you may develop side effects that were never a problem before. Benadryl is not intended to be used as a daily, long-term medication for sleep or other issues.Jun 14, 2023 · The symptoms you have noticed are very likely the result of long-term heavy antihistamine use. Antihistamines tend to dry up the nose, which is why they are so effective in humans with allergic rhinitis, but the way they do that is by making the secretions thicker. In dogs, we are not worried much about a runny nose, but we are concerned about ... Benadryl may cause serious side effects including: pounding heartbeats or fluttering in your chest, painful or difficult urination, little or no urination, confusion, lightheadedness, tightness in your neck or jaw, and. uncontrollable movements of your tongue. Get medical help right away, if you have any of the symptoms listed above.Jan 10, 2023 · hoarseness. lack or loss of strength. pain in the lower back or side. swelling of the hands, feet, or lower legs. trembling or shaking. Common side effects that do require medical attention ... Jul 31, 2023 · Extrapyramidal side effects (EPS), commonly referred to as drug-induced movement disorders are among the most common adverse drug effects patients experience from dopamine-receptor blocking agents. It was first described in 1952 after chlorpromazine-induced symptoms resembling Parkinson disease.[1] A variety of movement phenotypes has since been described along the EPS spectrum, including ... Diphenhydramine or : Benadryl (diphenhydramine) may cause sedation the next day (due to its long half-life), decreased alertness, diminished cognitive function, delirium, ... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5k views Reviewed >2 years ago.The phase IV clinical study analyzes which people take Benadryl and have Peripheral neuropathy. It is created by eHealthMe based on reports of 70,795 people who have side effects when taking Benadryl from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.Oct 3, 2022 · Adults and children ≥12 years of age receiving conventional or orally disintegrating tablets: Headache, somnolence, fatigue, dry mouth. Fixed combination loratadine (the active ingredient contained in Claritin) pseudoephedrine sulfate preparations: Insomnia, dry mouth, headache, somnolence, nervousness, dizziness, fatigue. Yeah, look at r/dph.Datura is even worse. It's like dph, but way more likely to kill you or make you go blind. Shadow people and spiders and having full conversations with people who don't exist usually only happens in the 400+ category. Between 150mg and there, it's usually just having to piss but being unable to, dysphoria/fear, be Jan 24, 2018 · Taking an over-the-counter sleep aid with diphenhydramine once in a while is generally not going to cause problems, other than a possible hangover the next day. Older people, however, can get confused when taking diphenhydramine because it also blocks a brain chemical called acetylcholine, which plays a big role in attention and short-term memory. Sleep aids: The options. Sleep aids available without a prescription are widely available. Common choices and the potential side effects include: Diphenhydramine (Benadryl). Diphenhydramine is a sedating antihistamine. Side effects might include daytime drowsiness, dry mouth, constipation and urinary retention. Doxylamine (Unisom).What are the side effects of Benadryl ... Diphenhydramine is only for short-term use until your symptoms clear up. ... (such as a long car ride, airplane or boat travel, amusement park rides, etc ...Inhaled corticosteroids are often used daily as part of treatment for asthma caused or complicated by reactions to airborne allergy triggers (allergens). Side effects are generally minor and can include mouth and throat irritation and oral yeast infections. Some inhalers combine corticosteroids with long-acting bronchodilators.Long term use of some antihistamines may increase your risk of dementia. Diphenhydramine (Benadryl®) blocks the effects of a neurotransmitter called acetylcholine. This neurotransmitter is vital for memory and learning. Diphenhydramine increased the risk of dementia by 54% in one 3,000 patient study followed for seven years.Feb 6, 2023 · Benadryl is an over-the-counter antihistamine that contains the active ingredient diphenhydramine. People often use it to treat allergies. Because it causes drowsiness, some people take it as a ... Apr 11, 2023 · In the drug realm, antihistamines such as diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), cetirizine (Zyrtec), and loratadine (Claritin) can help with a stuffy nose are safe for the heart. Nasal sprays deliver a decongestant right where you need it. In theory, this should minimize cardiovascular effects. Apr 8, 2023 · The main long-term side effects of Plaquenil are eye-related. ... To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine ... Jun 23, 2009 · The most common side effect is drowsiness, causing mild disorientation or dementia. An elderly person may fall asleep during normal activities. This sedating effect can cause unsteadiness. A person over 60 should get up slowly from a sitting or prone position to avoid fainting. If you take an anti-anxiety drug, it is not advisable to use ... “Atarax (hydroxyzine) and Benadryl (diphenhydramine) were routinely administered in the chemotherapy I received for breast cancer. After 5 months of chemo, I attributed my loss of mental function to a condition I read about called “chemo brain” — and chalked it up as another price paid in side affects for the benefit of staying alive.“The antihistamine diphenhydramine is only approved for management of short-term or temporary sleep difficulties, particularly in those people who have problems falling asleep,” Dr. What are the negative effects of Benadryl? Drowsiness, dizziness, constipation, stomach upset, blurred vision, or dry mouth/nose/throat may occur. If any of ...Dec 1, 2022 · Section snippets Sedation. The sedation associated with diphenhydramine is one of the most acknowledged effects of this medication. Indeed, it is frequently used as a medication to treat insomnia. 3 The sedative effect of diphenhydramine is related to its easy penetration of the blood-brain barrier. 4 In the brain, diphenhydramine interferes with H 1 receptors, which causes drowsiness and ... May 13, 2021 · The active ingredient in Benadryl is called diphenhydramine. Like any medication, Benadryl has several side effects. Some of the most common are: feeling sleepy or drowsy. dry mouth or throat ... Sleep aids: The options. Sleep aids available without a prescription are widely available. Common choices and the potential side effects include: Diphenhydramine (Benadryl). Diphenhydramine is a sedating antihistamine. Side effects might include daytime drowsiness, dry mouth, constipation and urinary retention. Doxylamine (Unisom).Diphenhydramine or : Benadryl (diphenhydramine) may cause sedation the next day (due to its long half-life), decreased alertness, diminished cognitive function, delirium, ... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5k views Reviewed >2 years ago. Nov 24, 2022 · But it has quite a long list of possible side effects. In fact, the Canadian Society of Allergy and Clinical Immunology has given serious warnings about them, even for people. The organization issued a 2019 position statement about Benadryl. They advised against the drug because of the high risk of side effects and overdose. They said the drug ... Apr 23, 2021 · Hives. Swelling and inflammation. Redness. Runny nose and eyes. Coughing. Sneezing. Anaphylactic reaction. One of the side effects of Benadryl is drowsiness, which can help to calm anxious dogs ... Benadryl and Depression. Although there is no direct effect of Benadryl on depression, regular and daily use of Benadryl does result in severe depression in the individual. It is believed to be helpful only for the short term, however, long term use of Benadryl results in certain depressive symptoms in the individual.Section snippets Sedation. The sedation associated with diphenhydramine is one of the most acknowledged effects of this medication. Indeed, it is frequently used as a medication to treat insomnia. 3 The sedative effect of diphenhydramine is related to its easy penetration of the blood-brain barrier. 4 In the brain, diphenhydramine interferes with H 1 receptors, which causes drowsiness and ...Diphenhydramine, which is the active ingredient in ZzzQuil, can cause side effects in some people. The most common side effects of diphenhydramine include: drowsiness. dizziness. loss of ...May 25, 2023 · Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Not able to pass urine or change in how much urine is passed. A very bad skin reaction ( Stevens-Johnson syndrome / toxic epidermal necrolysis) may happen. Uses Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough,...Overdosing on diphenhydramine (Benadryl) can also lead to more serious side effects like severe confusion, seizures, low blood pressure, involuntary muscle spasms, hallucinations (seeing things that aren't there), and heart rhythm problems. In fact, the FDA released a warning to avoid high doses of diphenhydramine.Some dosage forms listed on this page may not apply to the brand name Benadryl Allergy. Summary. More frequent side effects include: sedated state and thickening of bronchial secretions. Continue reading for a comprehensive list of adverse effects. Applies to diphenhydramine: oral capsules and tablets, parenteral injection. Side effects include:Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache.• Common side effects of montelukast include upper respiratory infection, fever, headache, sore throat, cough, stomach pain, diarrhea, earache or ear infection, flu, runny nose, and sinus infection. Common Benadryl (diphenhydramine) side effects include drowsiness, dizziness, and blurry vision. Dry mouth and constipation are common, as well. Serious Benadryl side effects include a greater risk of falls — especially if you are an older adult — and potential long-term memory problems.Nov 14, 2022 · A 2017 study revealed that 10% of adults aged 18-45 use OTC sleep aids while 17.5% of people 65 years and older do. Most over-the-counter options are considered safe when used occasionally—as long as the medication is compatible with any medical conditions you have and other medications you take. But when taken night after night, trouble can ... Jan 10, 2023 · hoarseness. lack or loss of strength. pain in the lower back or side. swelling of the hands, feet, or lower legs. trembling or shaking. Common side effects that do require medical attention ... Besides having side effects including drowsiness, confusion, and urinary retention, a new study shows that frequent, long-term use of older antihistamines are associated with an increased risk of ...The short answer seems to be yes. While occasionally taking a Benadryl for sleep probably won’t lead to significant weight gain, chronic use of antihistamines can interfere with weight loss efforts. If you need an antihistamine for frequent allergy symptoms, however, the best choice is Claritin because it does not cross into the brain and has ...Long-term side effects Over-the-counter Benadryl is approved for temporary or short-term use and is not intended for long-term use. There is very little scientific research about the long-term ...Jan 24, 2018 · Taking an over-the-counter sleep aid with diphenhydramine once in a while is generally not going to cause problems, other than a possible hangover the next day. Older people, however, can get confused when taking diphenhydramine because it also blocks a brain chemical called acetylcholine, which plays a big role in attention and short-term memory. Long-term use of Benadryl can also lead to constipation and confusion. Interactions. Benadryl containing diphenhydramine can interact with alcohol as both are central nervous system (CNS) depressants. Side effects such as drowsiness and dizziness may be enhanced when taking alcohol with diphenhydramine.Dear Alice, I've experimented with the abuse of Benadryl on a few occasions now and have been absolutely blown off to another world, I was just curious as to what the side affects, long or short-term, can look like, and what the dangers are of abusing this drug (acetaminophen free).Nov 24, 2022 · But it has quite a long list of possible side effects. In fact, the Canadian Society of Allergy and Clinical Immunology has given serious warnings about them, even for people. The organization issued a 2019 position statement about Benadryl. They advised against the drug because of the high risk of side effects and overdose. They said the drug ... May 7, 2021 · There is evidence that the use of diphenhydramine among older adults or the elderly may result in serious side effects. This holds true esp. if you are older than age 65. The older a person becomes, the greater the risk of adverse effects. Benadryl is listed as potentially Inappropriate Medication in Older Adults ( also known as Beers criteria) Higher dosage or long-term use of common drugs with anticholinergic effects is linked to significantly increased risk of dementia - including Alzheimer’s - says large study.Jan 10, 2023 · hoarseness. lack or loss of strength. pain in the lower back or side. swelling of the hands, feet, or lower legs. trembling or shaking. Common side effects that do require medical attention ... Sep 14, 2022 · Benadryl helps reduce the effects of natural chemicals in the body called histamines. It is used to treat the side effects of an allergic reaction, including: Benadryl can be taken to relieve the symptoms of hayfever (seasonal allergies) and motion sickness. It can also be taken to induce sleep and treat certain symptoms of Parkinson's disease.

Uses Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough,.... She hulk r34

benadryl side effects long term

Experts say skip antihistamines. Dana Benson. 713-798-8267. Houston, TX - Jun 28, 2021. Share this article. For people who take an antihistamine such as Benadryl for a cold or allergies, drowsiness is often a welcome side effect. But a Baylor College of Medicine sleep expert cautions against turning to this type of medication as a sleep aid.Take one to two 50mg tablets at least 30 minutes prior to bedtime. The maximum dose of two tablets works best for sleep. You can take Dramamine with or without food, but make sure you take a dose with a full glass of water 1 2. Swallow tablets whole; don't crush or chew. Plan on taking Dramamine four to six hours prior to waking for the next ...Diphenhydramine is a type of medicine called an antihistamine. It is used in some allergy and sleep medicines. Overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. This article is for information only. DO NOT use it to treat or manage an actual overdose. Diphenhydramine or : Benadryl (diphenhydramine) may cause sedation the next day (due to its long half-life), decreased alertness, diminished cognitive function, delirium, ... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5k views Reviewed >2 years ago.Common Benadryl (diphenhydramine) side effects include drowsiness, dizziness, and blurry vision. Dry mouth and constipation are common, as well. Serious Benadryl side effects include a greater risk of falls — especially if you are an older adult — and potential long-term memory problems.Oct 6, 2015 · Caution should be exercised for long-term use of Benadryl (diphenhydramine), an antihistamine and a non-benzodiazepine sedative-hypnotic, because of the association of increased risk for dementia. Yeah, look at r/dph.Datura is even worse. It's like dph, but way more likely to kill you or make you go blind. Shadow people and spiders and having full conversations with people who don't exist usually only happens in the 400+ category. Between 150mg and there, it's usually just having to piss but being unable to, dysphoria/fear, beCommon Side Effects of Diphenhydramine. Diphenhydramine is considered an H1 receptor antagonist, and it works by blocking the effect of histamine in the body. The chemical reactions that diphenhydramine trigger in the body can cause other potentially significant sedative side effects on the central nervous system (CNS).Benadryl dosage for dogs. The correct dosage of diphenhydramine for dogs depends on their weight. A small dog will need much less than a big dog to receive the same positive effects. According to ...skin rash. swollen joints. stomach discomfort, upset or pain. tender swollen glands in neck. tremor. unusual excitement, nervousness, restlessness, or irritability. vomiting. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.and readily penetrates the blood-brain-barrier. Thus side effects such as grogginess, drowsiness, and memory loss are common. Diphenhydramine is also used for motion sickness and extrapyramidal symptoms in Parkinson’s disease patients. Potential harm to the brain: Long-term anticholinergic use has been associated with increasedAug 1, 2023 · skin rash. swollen joints. stomach discomfort, upset or pain. tender swollen glands in neck. tremor. unusual excitement, nervousness, restlessness, or irritability. vomiting. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Oct 3, 2022 · Applies to diphenhydramine: oral capsules and tablets, parenteral injection. Side effects include: Sedation, sleepiness, dizziness, disturbed coordination, epigastric distress, thickening of bronchial secretions. Oct 6, 2015 · Caution should be exercised for long-term use of Benadryl (diphenhydramine), an antihistamine and a non-benzodiazepine sedative-hypnotic, because of the association of increased risk for dementia. Jul 5, 2023 · Benadryl is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and relieve some symptoms of Parkinson's disease. Sedation is a common side effect. 5. Tips. Benadryl may be taken with or without food. Take exactly as directed. First-generation antihistamines come with an increased risk of certain side effects and drug interactions, so they are not generally advised for long-term usage. “With first-generation antihistamines, some people note decreasing effectiveness if used daily for several days,” says Dr. Lin.While it may work to help you fall asleep for a few days, long-term use of Benadryl as a sleep-aid likely isn't effective and is associated with several side effects like next-day drowsiness. Additionally, the long-term use of drugs like Benadryl in those 65 years old and over is linked with an increased risk of dementia..

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